(a) The pair 24,27 is interesting, as the greatest prime factor of them both is 3. However, there are no primes between them.
(b) The number 1 and prime numbers cannot form a pair with any smaller integers. However, each composite number forms a pair with its greatest prime factor, which is clearly smaller. Among the first 25 positive integers, the primes are 2,3,5,7,11,13,17,19 and 23. Taking into account also the number 1, there are 10 numbers among the first 25 positive integers that don't form an interesting pair with any smaller positive integer.