Solution:
Answer: 4019
Let Brian's roll be d and let George's rolls be x,y,z. By pairing the situation d,x,y,z with 21−d,7−x,7−y,7−z, we see that the probability that Brian rolls higher is the same as the probability that George rolls higher. Given any of George's rolls x,y,z, there is exactly one number Brian can roll which will make them tie, so the probability that they tie is 201. So the probability that Brian wins is 21−201=4019.