Solution:
Without loss of generality assume that the left end of the first domino is red. Then, we have two cases:
If the first domino is red-red, this forces the second domino to be red-blue. The third domino cannot be blue-red, since the fourth domino would then be forced to be blue-blue, which is impossible. However, RR RB BB BR works.
If the first domino is red-blue, then the second domino cannot be blue-red, since otherwise there is nowhere for the blue-blue domino to go. Therefore, the second domino is blue-blue, which forces the third to be blue-red, and forces the fourth to be red-red. This yields one possibility.
Therefore, if the first color is red, there are 2 possibilities. We multiply by 2 to yield 4 total possibilities.