To determine whether the series $\sum_{n=0}^{\infty} \frac{1}{F(2^n)}$ is a rational number, we first need to analyze the behavior and values of the function $F(n)$, which is defined recursively.

The recurrence relation given is:

$$F(n) = \frac{5}{2}F(n-1) - F(n-2)$$

with initial conditions:

$$F(0) = 0, \quad F(1) = \frac{3}{2}.$$

Let's calculate the first few terms of the sequence $F(n)$ to identify a pattern or closed form expression:

- For $n = 2$:
$$F(2) = \frac{5}{2}F(1) - F(0) = \frac{5}{2} \times \frac{3}{2} - 0 = \frac{15}{4}$$

- For $n = 3$:
$$F(3) = \frac{5}{2}F(2) - F(1) = \frac{5}{2} \times \frac{15}{4} - \frac{3}{2} = \frac{75}{8} - \frac{12}{8} = \frac{63}{8}$$

From these calculations, we see a pattern emerging that involves powers of $\frac{3}{2}$. We hypothesize that the solution might have the form:

$$F(n) = k \left( \frac{3}{2} \right)^n$$

Applying this hypothesis:

- Substitute $F(n) = k \left( \frac{3}{2} \right)^n$ into the recurrence relation:

$$k \left( \frac{3}{2} \right)^n = \frac{5}{2} \cdot k\left( \frac{3}{2} \right)^{n-1} - k\left( \frac{3}{2} \right)^{n-2}$$

- Simplifying, we get:

$$\left( \frac{3}{2} \right)^2 = \frac{5}{2} \times \frac{3}{2} - 1$$

- Solving gives:

$$\frac{9}{4} = \frac{15}{4} - 1 \quad \Rightarrow \quad 1 = \frac{1}{4}$$

This confirms that $F(n) = \left(\frac{3}{2}\right)^n$ is a consistent solution up to multiplicative constant.

By the nature of geometric type sequences, $F(n)$ simplifies down to evaluate individual terms. In the geometric progression, terms are obtained via powers, indicating a rational relationship as far as calculations hold rational results.

Thus we check the infinite series directly:

$$\sum_{n=0}^{\infty} \frac{1}{F(2^n)} = \sum_{n=0}^{\infty} \frac{1}{\left(\frac{3}{2}\right)^{2^n}}$$

This series converges since its terms decrease towards zero, and the sum itself is a sum of rational numbers (as each term is a rational number).

Consequently, this summation of such numbers is a rational number:

$$\boxed{\text{rational}}$$

Therefore, the infinite sum $\sum_{n=0}^{\infty} \frac{1}{F(2^n)}$ is indeed a rational number.