Solution:
Since ∠QAC=∡QDC=∠QPA, it follows by the converse of the tangent-chord angle theorem that the line AC is tangent to the circumcircle of the cyclic quadrilateral APRQ. By assumption, AB is also tangent to the circumcircle of the cyclic quadrilateral AQCD, so the angles ∠ADQ and ∠PAQ are equal in size. From this it follows that ∠ACQ=∠ADQ=∠PAQ=∠CRQ, so AC is also tangent to the circumcircle of triangle CQR.

The intersection point M of the lines RQ and AC thus satisfies, by the secant-tangent theorem, ∣MA∣2=∣MQ∣⋅∣MR∣=∣MC∣2, so M is the midpoint of the segment AC, and hence also the midpoint of the segment BD.
Pappus's theorem, applied to the respectively collinear points A,B,P and R,Q,M, now implies that the intersection point S of the lines AQ and BR, C (as the intersection point of the lines AM and PR), and D (as the intersection point of the lines BM and PQ) lie on a line, which is exactly the statement to be shown.