Answer. There does not exist such a set.
Proof. Assume that M={a,b,c,d,e} were such a set. As there are 20 differences of distinct members from M and 20 residue classes modulo 25 whose members are not divisible by 5, the two lines
1,2,3,4,6,7,8,9,11,12,13,14,16,17,18,19,21,22,23,24
and
a−b,a−c,a−d,a−e,b−a,b−c,b−d,b−e,…,e−d
contain the same numbers when considered modulo 25. Taking products, we get
−1≡x,y∈M,x=y∏(x−y)(mod25).
Note that this implies that no two members of M are congruent modulo 5. Setting
Ω(x1,x2,x3,x4,x5)=1≤i,j≤5,i=j∏(xi−xj)
for all integers x1,…,x5 the above congruence may be rewritten as
Ω(a,b,c,d,e)≡−1(mod25).
Claim. If x1,…,x5 are integers no two of which are congruent modulo 5, then
Ω(x1+5,x2,x3,x4,x5)−Ω(x1,x2,x3,x4,x5)
is a multiple of 25.
To see this, we note that this difference is ∏2≤i<j≤5(xi−xj) times
(x1−x2+5)2⋯(x1−x5+5)2−(x1−x2)2⋯(x1−x5)2.
The second factor is
≡((x1−x2)2+10(x1−x2))⋯((x1−x2)2+10(x1−x2))−(x1−x2)2⋯(x1−x5)2
≡10(x1−x2)⋯(x1−x5)⋅Ψ(mod25),
where Ψ denotes the sum of all four product involving three of the numbers x1−x2,…,x1−x4. So it suffices to show that Ψ is divisible by 5, and as the four differences x1−x2,…,x1−x4 coincide modulo 5 with the numbers 1,2,3,4 we do indeed have
Ψ≡1⋅2⋅3+1⋅2⋅4+1⋅3⋅4+2⋅3⋅4≡50≡0(mod5).
This concludes the proof of our claim. Note that as the function Ω is symmetric in its variables, a similar statement holds when 5 is added not to x1 but to any other of these variables. Applying this fact iteratedly and using symmetry again, we get
Ω(a,b,c,d,e)≡Ω(0,1,2,3,4)≡82944≡19(mod25),
whereby we have reached a contradiction. This solves our problem.