2. [0,4].
(Method 1) It is easy to see that
2x+2−22x+1+2x+10−62x+1=(2x+1)2−22x+1+12+(2x+1)2−62x+1+32=∣2x+1−1∣+∣2x+1−3∣⩾2,
where the equality holds if and only if 1⩽2x+1⩽3, i.e., x∈[0,4].
(Method 2) According to the problem, we can set
2x+2−22x+1=1−d,2x+10−62x+1=1+d,
From
{1−d⩾01+d⩾0
we get −1⩽d⩽1. By (2)2−(1)2, we get
2x+1=2−d,
Substituting into equations (1) and (2), we get
{1+(2−d)2+2(2−d)=1−d,9+(2−d)2+6(2−d)=1+d
which holds for all −1⩽d⩽1.
Therefore, the original equation holds as long as 2x+1=2−d∈[1,3], i.e., x∈[0,4].